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Periodic Table

Turning Inventions into Innovations

Services

Drug Discovery

 

  • Structure-based drug design

  • Hit identification and validation

  • Hit to lead/lead optimization

  • Candidate selection criteria

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Preclinical Development

 

  • Global CRO selection and management

  • Salt screening/salt selection

  • Physicochemical and solid state characterization

  • Non-GMP scale up and labelled-API for toxicology and bio-distribution evaluation

  • Preformulation and formulation development

 

Business Strategy

 

  • Development and research strategy

  • Preparation and review of scientific content for investor pitch decks, preliminary prospectus

  • Draft and review CDAs, NDAs, master service agreements, research partnership agreements

  • Scientific due diligence of companies for research or M&A opportunities

Chemistry, Manufacturing and Controls (CMC)

 

  • Global CMO selection and management

  • Drug substance and drug product stability protocols

  • Analytical method development and fit-for-purpose validation

  • cGMP drug substance and drug product manufacturing for Phase 1 and Phase 2 

  • Preparation and review CMC documentation for both FDA and Health Canada regulatory filings
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Intellectual Property

 

  • Competitive landscape analysis

  • Draft and review of scientific content for patent filings​

 

Areas of Expertise

Therapeutic Areas

 

  • Oncology

  • Antimicrobials

  • Inflammation

  • Rare diseases-nephrology & dermatology

  • Oral and topical medical cannabis product design and development

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Chemistry

 

  • Natural products

  • Heterocyclic chemistry

  • Asymmetric chemistry

  • Nucleosides and Nucleotides

  • Peptides

  • CRISPR/Cas gene editing

Drug Targets

 

  • Kinases

  • Methyltransferases

  • G-protein coupled receptors (GPCRs)

  • Endocannabinoid system

  • Rare monogenic disorders
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